The backbone positions for NTD residues involved in binding p53-tad (left) and ssDNA (right) are colored red, showing the binding sites overlap but are not identical.

Side chains and labels are shown for NTD residues that make up the basic cleft.

The NTD residues colored red in the p53-tad diagram are 17, 33, 41, 48, 55-56, 58-59, 61, 68, 87,89,91-93, and 99. The NTD residues colored red in the ssDNA diagram are 35, 41, 42, 46, 55, 59, 61-62, 86, 88-93, and 98.

The ribbon diagram for the NTD was adapted from the solution structure of hsRPA701-168, PDB accession file 1ewi.